PNOE Metabolic Testing

PNOĒ® Metabolic Testing for Cancer Survivors

Precision Metabolic Assessment for Personalized Recovery, Weight Management, and Longevity

PNOĒ metabolic testing is an advanced, non-invasive assessment that measures how your body uses oxygen and energy at rest and during activity. For cancer survivors, this data provides critical insight into metabolic health, mitochondrial function, and physiologic recovery—areas often disrupted by cancer treatment.

At our clinic, PNOĒ testing is used to guide personalized nutrition, exercise, and weight optimization strategies, tailored specifically to the unique metabolic challenges faced during survivorship.

Why Metabolic Testing Matters After Cancer

Cancer therapies—including chemotherapy, radiation, endocrine therapy, and immunotherapy—can cause long-lasting metabolic changes, such as:

  • Reduced resting metabolic rate
  • Insulin resistance and altered fat metabolism
  • Loss of lean muscle mass
  • Persistent fatigue and exercise intolerance
  • Difficulty achieving or maintaining a healthy weight

Standard “one-size-fits-all” diet and fitness recommendations often fail cancer survivors. PNOĒ testing allows us to move from generalized advice to data-driven, individualized metabolic care.

What PNOĒ Measures

PNOĒ uses indirect calorimetry and respiratory gas analysis to assess:

  • Resting Metabolic Rate (RMR): Your true daily caloric needs
  • Fuel Utilization: Whether your body is burning fat or carbohydrates at various activity levels
  • VO₂ and metabolic flexibility: Indicators of cardiovascular and mitochondrial efficiency
  • Personalized heart rate zones: For safe and effective exercise prescription

These measurements form the foundation of a precision survivorship plan.

How PNOĒ Supports Cancer Survivorship

Medical Weight Management

Many survivors—particularly those on estrogen blockers or steroids—struggle with weight gain despite disciplined efforts. PNOĒ identifies metabolic inefficiencies that may be preventing progress and informs targeted nutrition and activity strategies.

Fatigue and Functional Recovery

By identifying inefficient energy utilization, PNOĒ helps guide interventions to improve stamina, strength, and daily functioning without overtraining or exhaustion.

Lean Mass Preservation

Loss of muscle is a major predictor of poor long-term outcomes. Metabolic testing supports muscle-preserving exercise and protein strategies, essential for survivorship health.

Cardiometabolic Risk Reduction

Cancer survivors are at increased risk of diabetes and cardiovascular disease. PNOĒ enables early identification of metabolic risk patterns and proactive intervention.

What to Expect During Testing

PNOĒ testing is safe, non-invasive, and typically takes 30–45 minutes. You will breathe through a mask while resting and/or performing light activity as directed by our clinical team. Results are reviewed in detail and translated into clear, actionable recommendations.
Testing is appropriate for most cancer survivors and is customized based on treatment history, current medications, and physical capacity.

Integration Into Comprehensive Survivorship Care

PNOĒ metabolic testing is a cornerstone of our integrative survivorship programs, often combined with:

  • Physician-guided medical weight loss
  • Exercise prescriptions tailored to treatment history
  • Nutritional strategies aligned with metabolic data
  • Supportive therapies to optimize recovery and resilience

This approach allows us to address survivorship not just as “life after cancer,” but as an opportunity for intentional physiologic optimization.

Our Philosophy

Cancer survivorship demands more than generic lifestyle advice. PNOĒ metabolic testing reflects our commitment to precision medicine, individualized care, and long-term health optimization—delivered with the same rigor as active cancer treatment.

This is survivorship care beyond the standard of care.

Schedule a Metabolic Assessment

To learn whether PNOĒ metabolic testing is right for you, we invite you to schedule a comprehensive survivorship consultation with our medical team